Article

BioGPT-ClinVar: Parameter-Efficient Fine-Tuning of a Biomedical LLM for Genomic Variant Interpretation

2026-07-01

Abstract excerpt

<title>Abstract</title> <p>Accurate interpretation of genomic variants remains a major challenge in precision medicine due to the increasing volume of sequencing data and the complexity of clinical annotation. Recent advances in biomedical large language models (LLMs) provide new opportunities for developing scalable approaches to genomic interpretation; however, the adaptation of such models to clinically annota...

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Literature Corpus work: 819cc22b-e7a6-5f3e-916e-e6118a057b64
DOI: 10.21203/rs.3.rs-10196893/v1

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