Article

Control of cortical population activity with patterned microstimulation

2026-03-04

Abstract excerpt

Closed-loop control of cortical activity is a central goal in systems neuroscience and clinical neuromodulation, but most approaches either rely on detailed circuit models that are unattainable in vivo or on open-loop stimulation tuned by trial and error. Here we introduce REACHable manifold Control (REACH-Ctrl), a data-driven brain–computer interface that achieves real-time control of population spiking activity...

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Literature Corpus work: 810992ca-5b16-57fe-aa40-7b8c1a28dec6
DOI: 10.64898/2026.03.02.709018

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