Article

Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors

2021-03-22

Abstract excerpt

Successful therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have harnessed the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Evidence that SARS-CoV-2 exists as locally evolving variants suggests that immunological differences may impact the effectiveness of antibody-based treatments such as convalescent plasma and vaccines. Considering that near-sourced convalesc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 80da43bf-1353-5961-bd2b-563a15c713dd
DOI: 10.1101/2021.03.19.21253975

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donorsDOI 10.1101/2021.03.19.21253975Read

Treatment of COVID-19 Patients with Convalescent Plasma in Houston, TexasSemantic proximity Read

Convalescent Plasma Therapy for COVID-19: A Graphical Mosaic of the Worldwide EvidenceSemantic proximity Read

Locally harvested Covid-19 convalescent plasma could probably help combat the geographically determined SARS-CoV-2 viral variants.Semantic proximity Read

Association of Convalescent Plasma Treatment with Reduced Mortality and Improved Clinical Trajectory in Patients Hospitalized with COVID-19 in the Community SettingSemantic proximity Read

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor populationSemantic proximity Read

HLA and red blood cell antigen genotyping in SARS-CoV-2 convalescent plasma donorsSemantic proximity Read

Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent PlasmaSemantic proximity Read

A randomized, double-blind, controlled trial of convalescent plasma in adults with severe COVID-19Semantic proximity Read

COVID-19 Convalescent Plasma Outpatient Therapy to Prevent Outpatient Hospitalization: A Meta-analysis of Individual Participant Data From Five Randomized TrialsSemantic proximity Read

Cohort profile: A Québec-based plasma donor biobank to study COVID-19 immunity (PlasCoV)Semantic proximity Read

Prolonged viral RNA shedding after COVID-19 symptom resolution in older convalescent plasma donorsSemantic proximity Read

COVID-19 convalescent plasma and randomized clinical trials: explaining conflicting outcomes and finding signals of efficacySemantic proximity Read