Article

Modeling the Effectiveness of Antibiotic Therapies Against Sepsis Using Continuous-time Hidden Markov Models

2026-07-10

Abstract excerpt

Patients suffering from sepsis need to be treated with an effective antibiotic therapy within the first hour after sepsis onset to decrease their risk of death. Microbiological data that provide information about the suitability of antibiotic therapies, however, is usually available only after 72 hours. Consequently, the treating physicians need to judge a therapy’s effectiveness based on the patients’ measured he...

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Literature Corpus work: 8067efb4-fe1f-54a4-a084-e8f283fb1774
DOI: 10.64898/2026.07.03.26357092

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