Article

EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

2020-12-21

Abstract excerpt

<h4>ABSTRACT</h4> Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor cell transcriptome. Strikingly, EBV miRNAs displayed exceptionally abundant expression in primary EBV-associated Burkitt’s Lymphomas (BLs) and Gastric Carcinomas (GCs). To investigat...

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Literature Corpus work: 804ae530-1a66-54a5-b61a-a1371a3fed5b
DOI: 10.1101/2020.12.21.423766

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