Evidence and Rationale for Centromedian Nucleus versus Internal Medullary Lamina Stimulation for Generalized Epilepsy Through Intra-Operative Multi-Modal Electrophysiology Studies

Abstract excerpt

<title>Abstract</title> <p>Epilepsy's global impact affects 65 million individuals, of which 30% endure drug-resistant epilepsy (DRE). Surgical excision of the epileptogenic zone remains the primary intervention but is often hampered if patients have generalized epilepsy. Neuromodulation, such thalamic centromedian nucleus (CM) neurostimulation, offers a promising alternative. However, the mechanism is unclear by...

Topics

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• Adolescent
• Brain Mapping
• Cerebrospinal fluid and hydrocephalus
• Child
• Electroencephalography
• Epilepsies, Partial
• Fetal and Pediatric Neurological Disorders
• Spinal Dysraphism and Malformations

Identifiers and source

Literature Corpus work

7d58eab7-0041-5025-971e-6d3cdf32f469

DOI

10.21203/rs.3.rs-4165053/v1