Article

Ophthalmologic findings in an induced model of Holoprosencephaly in zebrafish

2024-08-09

Abstract excerpt

Early forebrain development is a fascinating process. The fate of brain function but also the fate of visual perception largely depends on it. Holoprosencephaly (HPE) is the most frequent developmental disorder of the forebrain, during which the separation of the early precursor domains is hampered. A spectrum of clinical manifestations is seen with severe forms like alobar HPE and less severe forms like lobar HPE...

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Literature Corpus work: 7c9ecff5-d0ee-5939-a39e-bb36107ba9b7
DOI: 10.1101/2024.08.09.607329

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