Article

Pentoxifylline Enhances Sperm Quality, Reduces Oxidative Stress in Semen, and Decreases Sperm DNA Damage in Men with Asthenozoospermia Undergoing Assisted Reproductive Technology

2025-05-31

Abstract excerpt

Oxidative stress (OS) contributes to poor sperm parameters and increased sperm DNA fragmentation (sDF), yet effective therapeutic strategies remain limited. This study aimed to evaluate the in vitro efficacy of pentoxifylline (PTX) in improving sperm motility and reducing OS and sDF in men with isolated asthenozoospermia. Thirty semen samples from patients with asthenozoospermia were processed using density gradie...

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Literature Corpus work: 79f62e2d-321e-5831-b994-7a113eb8b4b3
DOI: 10.3390/oxygen5020008

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