Article

An integrated comparative physiology and molecular approach pinpoints mediators of breath-hold capacity in dolphins

2021-01-20

Abstract excerpt

Ischemic events, such as ischemic heart disease and ischemic stroke, are the number one cause of death globally. Ischemia prevents blood, carrying essential nutrients and oxygen, from reaching tissues and organ systems, leading to cell and tissue death, and eventual organ failure. While humans are relatively intolerant to these ischemic events, other species, such as marine mammals, have evolved remarkable toleran...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 79db19a6-b5e2-5d40-945e-b890ca7e511a
DOI: 10.1101/2021.01.20.425775

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An integrated comparative physiology and molecular approach pinpoints mediators of breath-hold capacity in dolphinsDOI 10.1101/2021.01.20.425775Read

Diving deep: understanding the genetic components of hypoxia tolerance in marine mammals.Semantic proximity Read

Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders.Semantic proximity Read

Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced diversSemantic proximity Read

Advances in molecular biology of hibernation in mammalsSemantic proximity Read

Molecular interactions underpinning the phenotype of hibernation in mammalsSemantic proximity Read

Differences in Tolerance to Hypoxia: Physiological, Biochemical, and Molecular-Biological CharacteristicsSemantic proximity Read

Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cellsSemantic proximity Read

Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic toleranceSemantic proximity Read

Tolerance to Ischemia—an Increasingly Complex BiologySemantic proximity Read

Deep Sequencing the Transcriptome Reveals Seasonal Adaptive Mechanisms in a Hibernating MammalSemantic proximity Read

Brain transcriptomes of harbor seals demonstrate gene expression patterns of animals undergoing a metabolic disease and a viral infectionSemantic proximity Read

Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins.Semantic proximity Read