Article

Hnrnpul1 controls transcription, splicing, and modulates skeletal and limb development in vivo

2020-02-04

Abstract excerpt

Mutations in RNA binding proteins can lead to pleiotropic phenotypes including craniofacial, skeletal, limb and neurological symptoms. Heterogeneous Nuclear Ribonucleoproteins (hnRNPs) are involved in nucleic acid binding, transcription and splicing through direct binding to DNA and RNA, or through interaction with other proteins in the spliceosome. We show a developmental role for Hnrnpul1 in zebrafish, resulting...

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Literature Corpus work: 793043f8-ae56-5164-92f5-e14235fec56e
DOI: 10.1101/2020.02.04.934257

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