Article

Exosomal miR-4644 targets SPRY3 to promote proliferation and invasion of pancreatic cancer

2026-01-05

Abstract excerpt

<title>Abstract</title> <p>Tumor-derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in exosome-mediated tumor progression in PC remains inadequately explored. This study demonstrates that miR-4644 upregulation in exosomes derived from PC promotes both proliferation and invasion, while its...

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Literature Corpus work: 77e3c838-bedd-5f47-bd65-4299bbc506aa
DOI: 10.21203/rs.3.rs-8338211/v1

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