Article

Integrating structural modeling and divergence dating of RNA-dependent RNA polymerases to resolve the evolutionary history of plant and fungal viruses: from sobemoviruses to sobelivirads

2024-11-15

Abstract excerpt

RNA-dependent RNA polymerases (RdRps) are crucial for RNA virus replication and serve as key marker genes for defining deep taxonomic ranks and for understanding viral evolutionary history. Despite their conserved functions and motifs, the high genetic diversity of RdRps complicates precise sequence comparisons across viral families, hindering accurate taxonomic classification of new species. Three-dimensional (3D...

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Literature Corpus work: 775a2216-b05f-5134-8aab-95d16a9c9fba
DOI: 10.1101/2024.11.13.623411

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