Article
EGR4-dependent decrease of UTF1 is associated with failure to reserve spermatogonial stem cells in infertile men
2021-02-02
Abstract excerpt
Despite the high incidence of male infertility, about 70% of infertile men do not receive a causative diagnosis. To gain insights into the regulatory mechanisms governing human germ cell function in normal and impaired spermatogenesis (cryptozoospermic patients, crypto), we combined single cell RNA sequencing (>30.000 cells), proteome, and histomorphometric analyses of testicular tissues. We found major alteration...
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Identifiers and source
- Literature Corpus work
- 75777a91-f9a7-5a29-b5c0-5b88bd89b40c
- DOI
- 10.1101/2021.02.02.429371