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Timing of transcriptomic peripheral blood mononuclear cell responses of sheep to <i>Fasciola hepatica</i> infection differs from those of cattle, reflecting different disease phenotypes

2021-06-22

Abstract excerpt

Infection with the zoonotic trematode Fasciola hepatica , common in many regions with a temperate climate, leads to delayed growth and loss of productivity in cattle, while infection in sheep can have more severe effects, potentially leading to death. Previous transcriptomic analyses revealed upregulation of TGFB1 , cell death and Toll-like receptor signalling, T-cell activation, and inhibition of nitric oxide p...

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Literature Corpus work
754dd69e-9100-57da-ac73-658e7f87fd61
DOI
10.1101/2021.06.21.449266
Open publication

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Timing of transcriptomic peripheral blood mononuclear cell responses of sheep to <i>Fasciola hepatica</i> infection differs from those of cattle, reflecting different disease phenotypesDOI 10.1101/2021.06.21.449266
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