Article

Extracting Phylogenetic Information of Human Mitochondrial DNA by Linear Autoencoder

2021-06-22

Abstract excerpt

We used a linear autoencoder (LAE) and its learning dynamics to analyze the high-order structure of human mitochondrial DNA (mtDNA). A total of 360 complete human mtDNA sequences were collected from the MITOMAP database and transformed into 1024-dimensional vectors of pentanucleotide frequencies. We compressed those into a three-dimensional (3D) coordinates by an LAE at each step of training by gradient descent wi...

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Literature Corpus work: 74ce8325-7ccf-5ba5-ba32-a819f19b184f
DOI: 10.1101/2021.06.22.449384

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