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Pregnancy and Early-Life Gut Virome in the Lifelines NEXT cohort: Origin, Persistence, Influencing Factors and Health Implications

2026-03-05

Abstract excerpt

The human gut virome is a key modulator of gut microbial ecology and function, yet its role in early gut ecosystem development remains poorly understood. Here, we profiled the DNA virome from 4,523 fecal and 91 breastmilk metagenomes from 714 mother–infant pairs in the Dutch birth cohort Lifelines NEXT. This analysis generated a catalog of 31,205 unique vOTUs, with 31,019 detected in fecal and 248 in breastmilk sa...

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Literature Corpus work
741cb64b-bf32-509b-9bcc-44faef61d315
DOI
10.64898/2026.03.05.709809
Open publication

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