Article

Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS

2023-12-21

Abstract excerpt

<h4>Background: </h4> Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 30,000 people in the United States. It is characterized by the progressive decline of the nervous system that leads to the weakening of muscles which impacts physical function. Approximately, 15% of individuals diagnosed with ALS have a known genetic variant that contributes to their disease. As therapies that s...

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Literature Corpus work: 73f75dad-3eb2-5d03-844b-bbf0cbaa8b0f
DOI: 10.21203/rs.3.rs-3721598/v1

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