Tuned to explore: Increased phasic responses to auditory targets and novelty in children regardless of induced tonic arousal

Abstract excerpt

The ability to focus on relevant information while ignoring distractions is critical during childhood, as it supports learning, social interaction, and adaptation to changing environments. This attentional balance is thought to depend in part on arousal regulation, mediated by the activity of the locus coeruleus norepinephrine (LC-NE) system. Moderate levels of arousal are typically associated with optimal cogniti...

Topics

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• Acoustic Stimulation
• Attention Deficit Hyperactivity Disorder
• Child, Preschool
• Cohort Studies
• Down Syndrome
• Electroencephalography
• Evoked Potentials, Auditory
• Intellectual Disability

Identifiers and source

Literature Corpus work

73c26403-1927-5cdf-80d5-9cbbb102f630

DOI

10.1101/2025.11.01.684607