Back to search

Article

MicroRNA-485-5p targets keratin17 to regulate pancreatic cancer cell proliferation and invasion via the FAK / SRC / ERK pathway

2023-04-04

Abstract excerpt

It is crucial to probe into the biological effect and mechanism of miRNA-485-5p regulating KRT17 in pancreatic cancer (PC) to understand its pathogenesis and identify potential biological targets. The bioinformatics means were used to evaluate the clinical significance of KRT17 expression in the TCGA database. TargetScan database analysis in conjunction with dual luciferase and RNA Immunoprecipitation (RIP) experi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
734ea613-dcc5-570d-b9d0-cd998fbbba2e
DOI
10.21203/rs.3.rs-2766483/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MicroRNA-485-5p targets keratin17 to regulate pancreatic cancer cell proliferation and invasion via the FAK / SRC / ERK pathwayDOI 10.21203/rs.3.rs-2766483/v1
KRT7 Overexpression is Associated with Poor Prognosis and Immune Cell Infiltration in Patients with Pancreatic AdenocarcinomaSemantic proximity
KRT17 Facilitates Proliferation, Migration and Invasion in Esophageal Squamous Cell Carcinoma by Regulating mTOR/S6K1 pathwaySemantic proximity
KRT17 Serves as an Oncogene and a Predictor of Poor Survival in Hepatocellular Carcinoma PatientsSemantic proximity
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancerSemantic proximity
Long noncoding RNA LINC00514 accelerates pancreatic cancer progression by acting as a ceRNA of miR-28-5p to upregulate Rap1b expressionSemantic proximity
LncRNA CASC19 contributed to the progression of pancreatic cancer through modulating miR-148b/E2F7 axis.Semantic proximity
KHSRP Stabilizes m6A-Modified Transcripts to Activate FAK Signaling and Promote Pancreatic Ductal Adenocarcinoma ProgressionSemantic proximity
CDK14/β-catenin/TCF4/miR-26b positive feedback regulation modulating pancreatic cancer cell phenotypes in vitro and tumor growth in mice model in vivo.Semantic proximity
nc‐RNA‐mediated high expression of CDK6 correlates with poor prognosis and immune infiltration in pancreatic cancerSemantic proximity
LncRNA-TUG1/EZH2 axis promotes cell proliferation, migration and the EMT phenotype formation through sponging miR-382Semantic proximity
Long noncoding RNA LINC00857 promotes pancreatic cancer proliferation and metastasis by regulating the miR-130b/RHOA axisSemantic proximity
Regulatory role of miRNAs in nasopharyngeal cancer involving PTEN/PI3K/AKT, TGFβ/SMAD, RAS/MAPK, Wnt/β‐catenin and pRB‐E2F signaling pathways: A reviewSemantic proximity
Select a neighboring publication to make it the new centre.