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Irreversible Alteration of Extracellular Vesicle and Cell-Free Messenger RNA Profiles in Human Plasma Associated With Ex Vivo Platelet Activation

2021-01-04

Abstract excerpt

The discovery and utility of clinically relevant circulating biomarkers depend on standardized methods that minimize preanalytical errors. Here, we examined the preanalytical variations of extracellular vesicles (EVs) and cell-free mRNA (cf-mRNA) profiles in human plasma and how post-freeze/thaw processing removes and retains EVs and cf-mRNA subtypes. Using multiparametric nanoscale flow cytometric analysis, which...

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Literature Corpus work
72b94ecf-d1ed-5c28-89a5-2ae628cfa96e
DOI
10.21203/rs.3.rs-133629/v1
Open publication

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Irreversible Alteration of Extracellular Vesicle and Cell-Free Messenger RNA Profiles in Human Plasma Associated With Ex Vivo Platelet ActivationDOI 10.21203/rs.3.rs-133629/v1
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