Article

Horizontal transfer of prokaryotic cytolethal distending toxin B genes to eukaryotes

2019-02-08

Abstract excerpt

Cytolethal distending toxins (CDTs) are tripartite eukaryotic genotoxins encoded in diverse bacterial and phage genomes. The cdtB subunit is a DNAse that causes eukaryotic cell cycle arrest and apoptosis, and in one context, is associated with resistance against parasitoid wasp infections. Here we report the discovery of functional cdtB copies in the nuclear genomes of insect species from two distantly related in...

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Literature Corpus work: 71d8bbad-2c7f-571c-988c-84cd2bca2618
DOI: 10.1101/544197

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