Article

Identifying Phelan-McDermid-Like Electrophysiological Subtypes in Autism Using EEG and Machine Learning

2026-05-04

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Phelan McDermid syndrome (PMS), caused by <italic>SHANK3</italic> haploinsufficiency, is a genetic form of autism spectrum disorder (ASD) that provides a genetically defined model for studying ASD-related circuit dysfunction. <italic>SHANK3</italic> mutations disrupt synaptic organization and cortical synchrony, leading to attenuated gamma-band auditory s...

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Literature Corpus work: 71726615-deee-50ad-a8ac-eaefc11af411
DOI: 10.21203/rs.3.rs-9456375/v1

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