Gut microbiota characteristics and its immunoregulatory role in inflammatory depression: joint clinical and animal data

Abstract excerpt

Previous studies have reported that inflammatory depression is a treatment-resistant depression subtype and that disturbed gut microbiota may be the source of low-grade inflammation. But the gut microbiota’s features and its role of immunoregulation in this subtype of depression remains uncertain. We propose that Toll-like receptor 4 (TLR-4)/nuclear factor kappa-B (NF-κB) and the Nod-like receptor family pyrin dom...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Gut microbiota and health
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

6d62b8fb-1ec8-55fa-a59d-57638f2de0b1

DOI

10.21203/rs.3.rs-3154268/v1