Article
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities
2021-08-16
Abstract excerpt
Shotgun metagenomics is a powerful tool to identify antimicrobial resistance (AMR) genes in microbiomes but has the limitation that extrachromosomal DNA, such as plasmids, cannot be linked with the host bacterial chromosome. Here we present a laboratory and bioinformatics pipeline HAM-ART (Hi-C Assisted Metagenomics for Antimicrobial Resistance Tracking) optimised for the generation of metagenome-assembled genomes...
Topics
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- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Pharmaceutical and Antibiotic Environmental Impacts
Identifiers and source
- Literature Corpus work
- 6d31ff1e-ab97-5dc1-a3ad-97cad558aed3
- DOI
- 10.1101/2021.08.16.456459
