Article

Is noxious stimulus-evoked electroencephalography response a reliable, valid, and interpretable outcome measure to assess analgesic efficacy in neonates? A systematic review and individual participant data (IPD) meta-analysis protocol

2024-06-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: There are several major challenges limiting our ability to test analgesic efficacy for treatment of neonatal pain, and progress in analgesic drug studies in neonates has stalled. One significant issue is the reliance of clinical pain assessments on traditional behavioural and vital signs-based measures and the exclusion of novel brain-based biomarkers. In this r...

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Literature Corpus work: 6c97a124-e375-5178-bbf3-8f248424cc6a
DOI: 10.21203/rs.3.rs-4464161/v1

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Is noxious stimulus-evoked electroencephalography response a reliable, valid, and interpretable outcome measure to assess analgesic efficacy in neonates? A systematic review and individual participant data (IPD) meta-analysis protocolDOI 10.21203/rs.3.rs-4464161/v1Read

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