Article
Identification of prognostic genes for hepatocellular carcinoma based on hepatocyte and ketone body metabolism using integrated bulk and single cell RNA sequencing
2026-04-22
Abstract excerpt
<title>Abstract</title> <p>Background The precise role of ketone body (KB) metabolism and the underlying cellular mechanisms in hepatocellular carcinoma (HCC) remain unclear. This study aimed to identify and mechanistically explore KB metabolism-related prognostic genes in HCC. Methods All data were obtained from public databases. Single-cell RNA sequencing (scRNA-seq) analysis and high-dimensional weighted gen...
Topics
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- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- FOXO transcription factor regulation
- Genomics, phytochemicals, and oxidative stress
- Hepatocellular Carcinoma Treatment and Prognosis
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 6c0a2646-0981-541b-b994-5554b3d767ab
- DOI
- 10.21203/rs.3.rs-9187321/v1
