Article

Literature-scaled immunological gene set annotation using AI-powered immune cell knowledge graph (ICKG)

2025-02-25

Abstract excerpt

Large scale application of single-cell and spatial omics in models and patient samples has led to the discovery of many novel gene sets, particularly those from an immunotherapeutic context. However, the biological meaning of those gene sets has been interpreted anecdotally through over-representation analysis against canonical annotation databases of limited complexity, granularity, and accuracy. Rich functional...

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Literature Corpus work: 6b7e6997-b2d8-5d36-8c1d-26583cefad16
DOI: 10.1101/2025.02.19.639172

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