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Cardiovascular Disease Pathogenicity Predictor (CVD-PP): A tissue-specific tool for discriminating pathogenicity cardiovascular disease gene variants

2023-07-06

Abstract excerpt

<title>Abstract</title> <p>Introduction. The interpretation of variants of uncertain significance (VUS) remains a challenge in the care of patients with established or familial cardiovascular diseases. 56% of potential variants within known cardiovascular risk genes are characterized as VUS and unbiased machine learning algorithms trained upon large data resources can stratify VUS into higher vs. lower probabili...

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Literature Corpus work
6ade2d9a-958e-52f3-8f86-c859c3d883b3
DOI
10.21203/rs.3.rs-3122220/v1
Open publication

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Cardiovascular Disease Pathogenicity Predictor (CVD-PP): A tissue-specific tool for discriminating pathogenicity cardiovascular disease gene variantsDOI 10.21203/rs.3.rs-3122220/v1
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