Article

Identification of autophagy-related genes for regulating cancer stem cell characteristics in colon adenocarcinoma by the analysis of transcriptome data stemness indices

2023-01-03

Abstract excerpt

The emergence of cancer stem cells (CSCs) is the barrier to effective clinical outcomes for Colon adenocarcinoma (COAD) patients. Autophagy was found to play an important role on CSCs stemness regulation. However, the specific role of autophagy-related genes in COAD stemness remains unclear. In this study, by processing on two independent stemness indices, mRNAsi and mDNAsi, TP53INP2 among 29 differentially expres...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6a74a3d7-6b29-5b93-86b0-4d3741dd1880
DOI: 10.21203/rs.3.rs-2401860/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of autophagy-related genes for regulating cancer stem cell characteristics in colon adenocarcinoma by the analysis of transcriptome data stemness indicesDOI 10.21203/rs.3.rs-2401860/v1Read

High Expression of TTK As Colon Stem Cell Marker Correlated With M1 Macrophages InfiltrationSemantic proximity Read

Prognostic value of autophagy-related genes based on single-cell RNA-sequencing in colorectal cancerSemantic proximity Read

Identification of Hub Genes to Control Cancer Stem cell Characteristics in Colon Adenocarcinoma Through Bioinformatics Analysis and Validation by Western BlottingSemantic proximity Read

Screening of immunosuppressive cells from colorectal adenocarcinoma and identification of prognostic markersSemantic proximity Read

ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing AnalysisSemantic proximity Read

Development of prognosis model for colon cancer based on autophagy-related genesSemantic proximity Read

Identification of tumor stem cell regulatory genes related to prognosis of colon cancer by co expression analysisSemantic proximity Read

Characterization of stem cell landscape and identification of stemness-relevant prognostic gene signature to aid immunotherapy in colorectal cancerSemantic proximity Read

Down-Regulation of an Autophagy-Related Gene SERPINA1 as a Superior Prognosis Biomarker Associates with Relapse and Distant Metastasis in Colon AdenocarcinomaSemantic proximity Read

Prognostic and Predictive Values of the Autophagy Signature in Colon CancerSemantic proximity Read

Weighted Gene Coexpression Network Analysis of Key Genes Controlling Cancer Stem Cell Characteristics by Mrnasi in Colon AdenocarcinomaSemantic proximity Read

Identification and Validation of a Novel Six-Gene Prognostic Signature of Stem Cell Characteristic in Colon CancerSemantic proximity Read