Article

Hypertensive posterior reversible encephalopathy syndrome in Lesch–Nyhan disease: possible contribution of chronic hyperuricemia and renin activation – a case report

2026-03-24

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<title>Abstract</title> <p>Background Posterior reversible encephalopathy syndrome (PRES) is characterized by seizures, altered consciousness, and vasogenic edema predominantly affecting the parieto-occipital regions. Although acute hypertension is a major precipitating factor, impaired cerebral autoregulation and endothelial dysfunction are also considered to contribute to its pathophysiology. Lesch–Nyhan disea...

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Literature Corpus work: 69279ce4-c3af-531e-ba21-aa77128ce130
DOI: 10.21203/rs.3.rs-9021501/v1

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