Article

Hotdogs and Beer: Dietary Nitrosamine Exposure Exacerbates Neurodevelopmental Effects of Ethanol in Fetal Alcohol Spectrum Disorder

2014-01-01

Abstract excerpt

In the immature brain, ethanol impairs insulin, insulin-like growth factor (IGF) and other trophic factor signaling, increases cellular stress, and impairs neuronal and glial functions. However, given the phenotypic heterogeneity of fetal alcohol spectrum disorder (FASD), which is not always ethanol dose-dependent, we hypothesized that cofactors modulate spectrum and severity of disease. Herein, we determined if N...

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Literature Corpus work: 678b9c48-a25b-5fc0-9101-7d05da6fcc07
DOI: 10.4303/jdar/235811

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