Article

Cathepsin-C (CTSC) Gene Mutations in Papillon-Lefevre Syndrome in India.

2020-02-26

Abstract excerpt

<h4>Background: </h4> Papillion Lefevre Syndrome (PLS) is a rare autosomal recessive disorder characterized by severe early onset periodontopathia and palmoplantar hyperkeratosis leading to premature loss of both primary and permanent dentition. PLS is caused by mutations in cathepsin C (CTSC) gene. The prevalence being 1-4 per million individuals with a carrier rate of 2 to 4 per million with no sex prediction an...

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Literature Corpus work: 6762d7f1-d233-5fc8-81e2-a4bd2bc869ee
DOI: 10.21203/rs.2.24653/v1

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