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Article

A novel mutation of the cathepsin C gene in a thai family with Papillon-Lefevre syndrome.

Journal of periodontology - 1 Mar 2005

Nitta Hiroshi, Wara-Aswapati Nawarat, Lertsirivorakul Jinda, Nakamura Tsutomu, Yamamoto Matsuo, Izumi Yuichi, Nakamura Toshiaki, Ishikawa Isao

Abstract excerpt

BACKGROUND: Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by palmar- plantar hyperkeratosis and rapid periodontal destruction of both primary and permanent dentitions. It has been shown that the disease is caused by cathepsin C gene (CTSC) mutation leading t...

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Source

Identifiers

PMID: 15857086
DOI: 10.1902/jop.2005.76.3.492

Genes

CTSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15857086-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A novel mutation of the cathepsin C gene in a thai family with Papillon-Lefevre syndrome.PMID 15857086Read ↗

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