Article

Oocyte-derived Factor GDF9 Suppresses Expression of StAR and CYP17A1 in Human Theca Cells

2021-10-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> GDF9 expression is decreased in the oocytes of PCOS ovaries when compared with that of normal controls at all developmental stages. The role of this change in excessive production of androgen in PCOS ovaries is unknown because the direct effect of GDF9 on androgen production in human theca cells remain unclear due to limited resources of human theca cells. <bold...

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Literature Corpus work: 66f5e5f5-0b68-5ff2-b92e-bb57fe1cdb2f
DOI: 10.21203/rs.3.rs-985462/v1

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