Article

Antiretroviral treatment is less effective at reducing gut microbiome-associated inflammation and T cell activation in people living with HIV in rural versus urban Zimbabwe

2023-08-31

Abstract excerpt

The widespread availability of antiretroviral therapy (ART) for people living with HIV (PLWH) has dramatically reduced mortality and improved life expectancy. However, even with suppression of HIV-1 replication, chronic immune activation and elevated inflammation persist. Chronic immune activation has been linked to a pro-inflammatory gut microbiome composition, exacerbated by compromised intestinal barrier integr...

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Literature Corpus work: 66f45b4c-79bf-574d-95aa-2526e4dd1938
DOI: 10.21203/rs.3.rs-3300723/v1

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