Article

Lipopolysaccharide composition determines the preferred route and entry kinetics of bacterial outer membrane vesicles into host cells

2016-11-01

Abstract excerpt

<h4>SUMMARY</h4> Outer membrane vesicles are microvesicles shed by Gram-negative bacteria and play important roles in immune priming and disease pathogenesis. However, our current mechanistic understanding of vesicle - host cell interactions is limited by a lack of methods to study the kinetics of vesicle entry and cargo delivery to host cells in real-time. Here, we describe a highly sensitive method to study the...

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Literature Corpus work: 665ed240-26b3-5996-8257-dec4770024cb
DOI: 10.1101/084848

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