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Transcriptome-Wide Identification of Hub Genes and Therapeutic Targets in Type 2 Diabetes Mellitus Through Integrated Bioinformatics and Molecular Docking-Based Drug Repurposing

2026-07-20

Abstract excerpt

<title>Abstract</title> <p>This study identified GLP1R as the strongest therapeutic target for T2DM through an integrated bioinformatics and molecular docking-based drug repurposing approach. Three independent microarray datasets of human pancreatic islet tissue (GSE20966, GSE25724, GSE41762) from the NCBI Gene Expression Omnibus were analysed to identify differentially expressed genes (DEGs) using GEO2R, and ove...

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Literature Corpus work: 657b4b84-1186-5f1e-bdf7-7e67c21898de
DOI: 10.21203/rs.3.rs-10381177/v1

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