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Proteomic Analysis of Rhesus Macaque Brain Explants Infected With Borrelia Burgdorferi Identifies Host GAP-43 As A Potential Factor Associated With Lyme Neuroborreliosis

2020-12-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Lyme neuroborreliosis (LNB) is one of the most dangerous manifestations of Lyme disease, but the pathogenesis and inflammatory mechanisms are not fully understood.<bold>Methods: </bold>Cultured explants from the frontal cortex of rhesus monkey brain (n=3) were treated with live <italic>Borrelia burgdorferi</italic> (Bb) or phosphate-buffered saline (PBS) for 6,...

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Literature Corpus work
65688100-fbf7-566a-839c-a5010b328d51
DOI
10.21203/rs.3.rs-126769/v1
Open publication

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Proteomic Analysis of Rhesus Macaque Brain Explants Infected With Borrelia Burgdorferi Identifies Host&nbsp;GAP-43 As A Potential Factor Associated With Lyme NeuroborreliosisDOI 10.21203/rs.3.rs-126769/v1
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