Article

Reduced sensitivity of commercial Spike-specific antibody assays after primary infection with the SARS-CoV-2 Omicron variant

2022-07-20

Abstract excerpt

<title>Abstract</title> <p>The SARS-CoV-2 Omicron variant is characterized by substantial changes in the antigenic structure of the Spike (S) protein. Therefore, antibodies induced by primary Omicron infection lack neutralizing activity against earlier variants. In this study, we analyzed whether these antigenic changes impact the sensitivity of commercial anti-SARS-CoV-2 antibody assays. Sera from 37 unvaccinate...

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Literature Corpus work: 65084068-d7aa-5ee9-88ff-4f8cbf6869c6
DOI: 10.21203/rs.3.rs-1669740/v4

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