Article

Next-gen vaccine design: Integrating proteomics and bioinformatics for japanese encephalitis

2025-01-01

Abstract excerpt

Japanese encephalitis is the most neglected tropical disease induced by a neuroinvasive flavivirus, which refers to the Japanese encephalitis virus (JEV). To date, no successful treatment strategies are available for this disease. Thus, utilizing immunoinformatics and reverse vaccinology, we designed a novel mRNA vaccine (JE-mVax) targeting the viral capsid protein, a precursor to the membrane M protein, and envel...

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Literature Corpus work: 64f76c50-7263-5e3d-a9bb-1e31335ebdb7
DOI: 10.1016/j.csbr.2025.100049

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