Identification and clinical implications of the immune-related hub genes in psoriasis

Abstract excerpt

<title>Abstract</title> <p>Methods: Multiple microarray datasets from psoriasis patients (GSE30999, GSE106992, GSE14905, GSE78097, and GSE117468) were obtained to identify immune-key genes by differential gene analysis and Weighted Gene Co-expression Network Analysis (WGCNA). Subsequently, immune-related hub genes were identified using the Least Absolute Shrinkage and Selection Operator (LASSO) algorithm and Prot...

Topics

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• Antifungal resistance and susceptibility
• Asthma and respiratory diseases
• Bioinformatics and Genomic Networks
• Biotin and Related Studies
• Cytokine Signaling Pathways and Interactions
• NF-κB Signaling Pathways
• Psoriasis: Treatment and Pathogenesis
• Retinoids in leukemia and cellular processes

Identifiers and source

Literature Corpus work

632a59be-d056-5fa2-bcca-0577065e5aa2

DOI

10.21203/rs.3.rs-5782804/v1