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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

2013-09-02

Abstract excerpt

Exosomes are nanosized (30-100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes. Because exosomes have been isolated from most body fluids they may provide a source for non-invasive cancer diagnostics. Transcriptome profiling that uses deep-s...

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Identifiers and source

Literature Corpus work
61b51427-b44b-52c4-a711-9b41eea05de6
DOI
10.7287/peerj.preprints.56v1
Open publication

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