Article

Microbiota-modulated spermine promotes brain metastasis in non-small cell lung cancer by regulating microglia M2 polarization via the STAT3 pathway

2022-11-30

Abstract excerpt

<title>Abstract</title> <p>Brain metastasis (BM) is associated with high mortality in patients with non-small cell lung cancer (NSCLC). Alterations in the gut microbiota have been implicated in modulation of brain disorders through the gut-brain-axis (GBA). However, the underlying mechanism by which the gut microbiota affects the development of BM in NSCLC remains largely unknown. In patients, we identified 16 ge...

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Literature Corpus work: 5f89bf18-1fb8-57a7-ae50-d65be770e672
DOI: 10.21203/rs.3.rs-2259805/v1

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