Article

Sporadic and Familial Variants in NF1: An Explanation of the Wide Variability in Neurocognitive Phenotype?

2020-01-07

Abstract excerpt

<title>Abstract</title><p>Background: Cognitive impairment is the most common neurological manifestation in NF1 and occurs in 30–70% of NF1 cases. The onset and severity of each specific cognitive deficit varies greatly from child to child, with no apparent external causes. The wide variability of phenotype is the most complex aspect in terms of management and care. Despite multiple research, the mechanism underly...

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Literature Corpus work: 5f84cdfb-a994-5f8c-8731-9f27cf582b13
DOI: 10.21203/rs.2.20221/v1

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