Article

Factors associated with long-term opioid therapy discontinuation for people with chronic non-cancer pain in UK primary care: a population-based retrospective cohort study

2025-03-20

Abstract excerpt

<h4>Objectives</h4> To identify factors associated with long-term opioid therapy (L-TOT) discontinuation in people with chronic non-cancer pain (CNCP). <h4>Design and setting</h4> Population-based retrospective cohort study using UK Clinical Practice Research Datalink Aurum data between 01/01/2000-31/12/2020. <h4>Population</h4> The study cohort comprised adults (≥18 years) with CNCP who were using L-TOT, defined...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5e6c2dfd-22c9-5f69-8191-cd58a227342b
DOI: 10.1101/2025.03.19.25324292

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Factors associated with long-term opioid therapy discontinuation for people with chronic non-cancer pain in UK primary care: a population-based retrospective cohort studyDOI 10.1101/2025.03.19.25324292Read

The effects of a provincial opioid prescribing standard on opioid prescribing for pain: interrupted series analysisSemantic proximity Read

Effectiveness of slow-release oral morphine versus other OAT regimens in key sub-populations: protocol for population-based target trial emulationSemantic proximity Read

Exploring Opioid Management Challenges in Chronic Non-Tumor Pain: Findings from a Mixed-Methods Study among General PractitionersSemantic proximity Read

Epidemiology of chronic pain and opioid use in primary care – a scoping review of big data researchSemantic proximity Read

Changes in opioid prescribing during the COVID-19 pandemic in England: cohort study of 20 million patients in OpenSAFELY-TPPSemantic proximity Read

Evaluating a primary care pharmacist-led intervention to reduce opioid use for persistent non-cancer pain: the PROMPPT cluster randomised controlled trial protocolSemantic proximity Read

POTENTIAL INAPPROPRIATE USE OF STRONG OPIOID ANALGESICS IN CANCER OUTPATIENTS DURING THE LAST YEAR OF LIFE IN FRANCE AND ASSOCIATED FACTORSSemantic proximity Read

Healthcare use by people who use illicit opioids (HUPIO): development of a cohort based on electronic primary care records in EnglandSemantic proximity Read

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022 - a repeated cross-sectional studySemantic proximity Read

Identifying high-risk comorbidities of short and long-term opioid prescription useSemantic proximity Read

Patterns of opioid use after surgical discharge: a multicentre, prospective cohort study in 25 countriesSemantic proximity Read

Factors influencing non-adherence to opioids in cancer patients: a mixed-methods cross-sectional studySemantic proximity Read