Article

Integrated protein-protein interaction and RNA interference screens reveal novel restriction and dependency factors for a tick-borne flavivirus in its human host

2022-11-04

Abstract excerpt

<h4>ABSTRACT</h4> In Europe, tick-borne encephalitis virus (TBEV) is responsible for severe neurological disease in humans. Like other viruses, TBEV is an obligate intracellular life form whose survival requires subversion of metabolic processes and evasion of anti-viral pathways. This feat is achieved in no small part by binary interactions between dedicated viral proteins and host proteins. Such protein-protein...

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Literature Corpus work: 5e60d36b-8423-5579-9816-1406b5600e3e
DOI: 10.1101/2022.11.03.514869

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