Article

Haploidentical Transplantation in a DNA Ligase IV Deficiency Patient: A Case Report and Review of The Literature

2021-09-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: DNA ligase IV (LIG4) deficiency is a rare autosomal recessive disorder caused by mutations in the DNA LIG4 gene. Nowadays hematopoietic stem cell transplantation(HSCT) is the most effective treatment option. Matched sibling or unrelated donor was the best choice for those patients. However, it will be a problem for LIG4 deficiency patients without proper donor a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5e207eb3-b92e-5ea4-904e-34428161d435
DOI: 10.21203/rs.3.rs-786496/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Haploidentical Transplantation in a DNA Ligase IV Deficiency Patient: A Case Report and Review of The LiteratureDOI 10.21203/rs.3.rs-786496/v1Read

Molecular and immunological characterization of DNA ligase IV deficiency.Semantic proximity Read

LIG4 Syndrome: Clinical and Molecular Characterization in a Chinese CohortSemantic proximity Read

A novel mutation in a family with DNA ligase IV deficiency syndrome.Semantic proximity Read

Ligase IV syndrome.Semantic proximity Read

Failing to Make Ends Meet: The Broad Clinical Spectrum of DNA Ligase IV Deficiency. Case Series and Review of the LiteratureSemantic proximity Read

LIG4 syndrome: clinical and molecular characterization in a Chinese cohort.Semantic proximity Read

DNA ligase IV syndrome; a review.Semantic proximity Read

Haematopoietic Stem Cell Transplantation for DNA Ligase 1 Deficiency.Semantic proximity Read

Characterization of a Cohort of Patients With LIG4 Deficiency Reveals the Founder Effect of p.R278L, Unique to the Chinese Population.Semantic proximity Read

Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failureSemantic proximity Read

DNA ligase IV dificiency with elevated serum IgG levels suspected to have myelodysplastic syndrome: a case report.Semantic proximity Read

Epstein–Barr virus‐associated B‐cell lymphoma in a patient with DNA ligase IV (LIG4) syndromeSemantic proximity Read