Integrated Multi-Omics and Network-Based Identification of Prognostic Cell-Cycle Hub Genes in Lung cancer

Abstract excerpt

<title>Abstract</title> <p>Lung cancer (LC) remains the leading cause of cancer-related mortality global, dictating the identification of novel predictive biomarkers for improved diagnosis and therapeutic targeting. In this article, transcriptomic analysis was performed using RNA-seq data retrieved from three publicly available GEO datasets (GSE81089, GSE40419 and GSE141569). Differentially expressed genes (DEGs)...

Topics

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• Bioinformatics and Genomic Networks
• Cancer Immunotherapy and Biomarkers
• Cancer Mechanisms and Therapy
• Ferroptosis and cancer prognosis
• Gene expression and cancer classification
• Lung Cancer Treatments and Mutations
• RNA modifications and cancer

Identifiers and source

Literature Corpus work

5d07e0f3-8332-5981-814d-072df870e56b

DOI

10.21203/rs.3.rs-10494308/v1