Article

Multidimensional Impairment in Multiple Sclerosis—Physical Disability, Cognitive Disfunction, Sleep Disturbance, Fatigue, Depression, and Their Impact on Quality of Life: Evidence of a Common Pathological Pathway

2025-09-18

Abstract excerpt

<h4>Background: </h4> Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, that can lead to physical and cognitive disability, fatigue, depression, and sleep disturbance, all of which may impair quality of life (QoL). While physical disability is well known influencing the QoL, the relative contributions of cognitive impairment, fatigue, and sleep quality remain incompletely def...

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Literature Corpus work: 5ad4bd95-6a72-5a8f-a619-72fce524284e
DOI: 10.20944/preprints202509.1585.v1

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