Article

De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of <i>Bbs1</i>

2023-10-03

Abstract excerpt

Bardet-Biedl syndrome (BBS) is an archetypal ciliopathy caused by dysfunction of primary cilia. BBS affects multiple tissues, including the kidney, eye and hypothalamic satiety response. Understanding pan-tissue mechanisms of pathogenesis versus those which are tissue specific, and gauging their associated inter-individual variation owing to genetic background and stochastic processes, is of paramount importance i...

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Literature Corpus work: 5a1461d2-60db-5cfd-9d6a-620fbf7db258
DOI: 10.1101/2023.10.02.560442

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